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PMIS : Latest post Covid-19 challenge for doctors

In a major cause of worry for doctors, several COVID-19 positive children in Mumbai are showing symptoms of a life threatening disorder. So far , two children have died after being diagnosed with the PMIS .

What is PMIS ?
Paediatric Multisystem Inflammatory Syndrome (PMIS) is a very rare , but serious inflammatory condition that affects the children. 



What are the symptoms of PMIS ?
Mild symptoms of PMIS include fever, cough, sore throat and a rash. It can also cause swelling of the hands, feet and lymph nodes. In more severe cases, PMIS can also affect blood pressure , the heart and the kidneys.

Symptoms of PMIS may not appear until several weeks after the initial infection. In some cases, families may not know their child had COVID-19 until they show symptoms of PMIS. In general , it is important to remember that symptoms of COVID-19 tend to be milder or do not appear as often in children.

What causes PMIS ?
The cause of PMIS is not known , but doctors think that it is related to a COVID-19 infection. The body's immune system may somehow cause severe inflammation in some children who are more likely to develop PMIS, based on their genetics. 

Is PMIS Contagious ? 
It seems to be a post -infection complication of COVID -19 , an illness that typically occurs up to several weeks after an initial infection and is therefore not contagious. Even if a child develops PMIS , test positive for COVID-19 and might be infectious to others, it is important to remember that a very small percentage of children with COVID-19 develops PMIS.

Diagnosis :
To diagnose PMIS a detailed history , a physical exam and a blood test is required. They may also do an echocardiogram (ultrasound) of the heart and other studies.

Best recommendation to treat PMIS : 
Not all children need medication, mil symptoms like fever, cough, or sore throat, can be treated at home with fluids and fever reducers, such as acetaminophen.
Hospitalized children with more severe symptoms of PMIS may be treated with medications to help their blood pressure, heart  function or to treat blood clots. They may also need inflammatory medications. If children have PMIS and COVID-19, they may also need blood products and antiviral therapy. 

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